Dr. Jeffrey Persson is a highly regarded reproductive endocrinologist and male infertility specialist, bringing over 30 years of experience in reproductive medicine. As a subspecialist in reproductive endocrinology and infertility, he provides advanced expertise in the hormonal, genetic, and clinical complexities that affect fertility in both men and women.
Male factor infertility contributes to roughly half of all infertility cases, making his expertise vital for couples seeking reproductive assistance. Dr. Persson’s primary practice is based at No.1 Fertility Sydney, Level 1, 33 York Street. He also consults with Melbourne patients when required, with appointments coordinated through No.1 Fertility’s Melbourne locations at Level 1, 1 Collins Street, and Level 2, 120 Jolimont Road, East Melbourne. This flexible arrangement allows Victorian patients to access his specialist knowledge without unnecessary interstate travel.
Dr. Persson holds an MD and Fellowship of the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (FRANZCOG). He also has a Certificate in Reproductive Endocrinology and Infertility (CREI), reflecting his recognised subspecialist status. Over his career, he has helped thousands of individuals and couples pursue their family-building goals.
Professional Background and Career Highlights
Dr. Persson’s career demonstrates a long-standing commitment to innovation and excellence in reproductive health. After completing medical training in Australia, he undertook advanced fellowships in the United Kingdom and United States, gaining exposure to leading-edge techniques in fertility treatment. Before joining No.1 Fertility, he served as Clinical Director at a major Sydney fertility centre, where he founded a dedicated male infertility unit, demonstrating his focus on this often-underrepresented area of care.
In 1998, Dr. Persson was a pioneer in Australia, becoming one of the first specialists to routinely implement blastocyst-stage embryo transfer in collaboration with embryologist David Mortimer. This technique, which involves culturing embryos to the blastocyst stage prior to transfer, facilitates superior embryo selection and has proven especially effective in cycles influenced by male factor infertility
Specialisation in Male Factor Infertility
Male factor infertility encompasses conditions such as:
· Oligospermia (low sperm count)
· Asthenozoospermia (reduced sperm motility)
· Teratozoospermia (abnormal sperm morphology)
· Azoospermia (absence of sperm in ejaculate)
Dr. Persson is recognised for his advanced expertise in managing these conditions with a combination of medical, surgical, and assisted reproductive techniques. He is highly skilled in microsurgical sperm retrieval, including testicular sperm extraction (TESE) and microdissection TESE (micro-TESE). These procedures are vital for men with non-obstructive azoospermia, enabling the recovery of viable sperm from testicular tissue, typically in conjunction with intracytoplasmic sperm injection (ICSI) during IVF to achieve fertilisation.
Dr. Persson’s diagnostic process combines advanced genetic screening, detailed hormonal assessments, and comprehensive semen analysis to create personalised treatment plans that target the root causes of male infertility. His approach aims to improve sperm quality where possible and optimise overall outcomes for IVF and other assisted reproductive treatments. At No.1 Fertility, he ensures that male partners are fully included in every step of the fertility evaluation, providing thorough assessments and customised strategies that integrate lifestyle guidance, targeted medical therapies, and advanced laboratory support.
Patient-Centred Care and Communication
Patients consistently highlight Dr. Persson’s clear, empathetic, and transparent communication style. He explains complex fertility concepts in accessible language, offers practical guidance, and adapts treatment plans to each patient’s individual circumstances.
Understanding the emotional and relational impact of fertility challenges, especially those involving male factors, Dr. Persson promotes a couple-centred approach. He encourages active involvement of both partners in assessments and treatment discussions and facilitates access to counselling and multidisciplinary support to help patients navigate the psychological and interpersonal aspects of fertility care.
Academic and Research Contributions
Dr. Persson actively contributes to education and research in reproductive medicine. He lectures at the University of Sydney, mentors emerging fertility specialists, and has published research on genetic causes of male infertility and surgical outcomes. His
work has been cited over 100 times and presented at national and international conferences, including those of the Australian and New Zealand Society of Reproductive Endocrinology and Infertility (ANZSREI).
He continues to integrate the latest scientific advancements into practice, including improvements in sperm cryopreservation, embryo culture, and microsurgical techniques.
Alignment with No.1 Fertility
At No.1 Fertility, Dr. Persson embodies the clinic’s doctor-led, patient-first philosophy. The clinic’s state-of-the-art facilities in Sydney, his primary base, and Melbourne ensure smooth, coordinated care from initial consultations through to advanced treatments. For Melbourne patients, the availability of consultations with Dr. Persson when required provides convenient access to his specialised expertise in male factor infertility.
Dr. Jeffrey Persson’s extensive expertise, revolutionary contributions in male factor infertility, and compassionate approach make him a valued member of the No.1 Fertility team. Whether assisting with male-specific fertility concerns or supporting broader reproductive journeys, he provides evidence-based, patient-centred guidance at every stage. Due to high demand, patients in Melbourne are encouraged to contact the clinic directly to discuss consultation options and schedule appointments.
Ready When You Are
Whether you are just starting to explore your options, have had tests elsewhere, or want a fresh assessment of male fertility, we’re here to help. Options include in-clinic or at-home semen analysis using the Sapyen kit.
At No.1 Fertility, we guide you with evidence-based care, personalised support, and clear communication. You’re never alone on your fertility journey, and we’re here to support every step toward building your family.
Book a consultation or get in touch:
· Sydney: (02) 8604 3499 or email sydney@number1fertility.com
· Melbourne: (03) 9132 9600 or email hello@number1fertility.com
