Embryo Genetic Testing in IVF: Do You Actually Need It?
Embryo genetic testing, known as preimplantation genetic testing (PGT), is one of the most talked about aspects of IVF, and often one of the least clearly explained.
Many patients are aware that embryo genetic testing is available but are unsure if any PGT option is right for their circumstances.
At No.1 Fertility, we take a considered approach. PGT is not routinely added to every IVF cycle. Instead, it is used selectively, when it is likely to provide information that will meaningfully guides the next step.
One of the most common misconceptions is that there is a single genetic test that covers everything. Genetic testing in fertility care involves a range of different approaches, each designed to answer a specific question.
In the general population, around 3 to 4% of babies are born with a genetic or structural condition. This risk can be higher in certain situations, particularly with advancing maternal age or when there is a known inherited condition in the family.
PGT allows embryos to be assessed before they are transferred. This can reduce the likelihood of transferring embryos with chromosome errors or known inherited genetic abnormalities and may provide greater clarity earlier in the process.
It is equally important to understand the limitations of PGT. Preimplantation genetic testing does not improve or change embryos. It helps us choose between them.
It does not:
- improve embryo quality
- guarantee pregnancy
- ensure a successful outcome
It is best understood as a decision-making tool, not a treatment. Its value lies in whether it changes what you do next.
Patients who may benefit from including embryo genetic testing in their treatment plan may have:
- Previous unsuccessful embryo transfers
- A history of miscarriage
- Increasing maternal age
- A known genetic condition within the family
In these contexts, PGT may help guide embryo selection and inform the next stage of care.
There are also situations where PGT may not significantly change the outcome. For younger patients with good embryo numbers, or in early IVF cycles without specific risk factors, adding genetic testing may not meaningfully alter decision-making.
This is where clinical judgement matters. Adding more steps does not always lead to better outcomes.
It is also worth recognising that embryo genetic testing does not occur in isolation, and there are limitations to what any genetic test can tell us. There are behind the scenes factors that are not always visible to patients, but they play an important role in ensuring the information obtained is reliable and clinically useful.
Preimplantation genetic testing can be a valuable part of IVF, but only when used for the right reason. The goal is not just to do more. It is to make informed decisions using the right information at the right time.
If you are unsure about whether embryo genetic testing is right for you, you can explore more information about the different types of PGT on our website, which has been developed by our team of experienced Genetic Counsellors.
No.1 Fertility also offer additional genetic testing options, including carrier screening and karyotype analysis. You can read more info or get in touch to discuss more.
If you would like personalised guidance, you can book a consultation with one of our Fertility Specialists or book a free chat with a Genetic Counsellor to explore what may be appropriate for you.
Ongoing Research and Expertise
Our Genetics team is actively involved in research and continuous professional development to ensure patients benefit from up-to-date, evidence-based care.
Genetic Counselling Manager Cheryl Tse recently presented research at the Preimplantation Genetic Diagnosis International Society (PGDIS) annual conference in Shanghai, where she was awarded the best oral presentation.
This reflects our team’s ongoing commitment to research, keeping up to date with latest technological developments and advances in clinical care. We look forward to sharing further insights at the upcoming Human Genetics Society of Australasia conference in Christchurch this August.
