Polycystic Ovarian Syndrome (PCOS)
DID YOU KNOW…?
Polycystic Ovarian Syndrome (PCOS) affects about 10% of women, disrupting hormones in ways that complicate conception. It’s typically diagnosed when at least two of these show up: irregular or absent ovulation (anovulation), elevated testosterone (hyperandrogenism), and ovaries packed with over 20 small follicles on ultrasound.
Why PCOS Knowledge Empowers You
PCOS isn’t just a label—it’s a roadmap to targeted fixes, as these traits directly stall egg release, hormone balance, and cycle regularity, slashing natural pregnancy odds. At No1 Fertility, we spot it early via patient history, exams, pelvic scans, and bloodwork, then craft custom Fast Track protocols—like ovulation induction or metformin tweaks—that outperform rigid corporate plans. This personalised approach helps women from other clinics who’ve battled one-size-fits-all treatments, restoring ovulation and boosting success without unnecessary delays.
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Symptoms of PCOS
• Irregular or missed menstrual periods
• Difficulty maintaining a healthy weight (50% of women with PCOS are overweight)
• Increased hair growth (hirsutism)
• Acne
• Infertility
• Thick endometrial lining (as the lining is not shed regularly which can lead to episodes of abnormal bleeding )
• Metabolic syndrome – which leads to elevated blood pressure, diabetes, increased risk of heart disease and obesity with increased weight around the abdomen
Investigations
• Hormone evaluation including male hormones such as testosterone often elevated
• Full blood examination with LFT (there is an increased risk of fatty liver)
• Lipid profile (often abnormal lipid profile is detected)
• Glucose testing
Treatment
- If pregnancy is not desired the oral contraceptive pill with an antiandrogen is the best form of treatment and prevention
- If pregnancy is desired, oral therapies such as clomid or letrozole can be used (although note there is 10% increased risk of a multiple pregnancy)
- Lifestyle changes are important, and a low carbohydrate diet should be followed
- Metabolic issues should be treated with metformin
- Where there is resistance to the use of clomid – ovarian drilling may be considered – a surgical procedure to burn the follicles – this comes with risk of scarring and damage to the ovary and its function
- Low dose Gonadotropins if oral agents do not induce ovulation (there is an increased risk of a multiple pregnancy of between 20-30 %)
- IVF is generally considered if ovulation therapy fails or if the patient wishes to avoid a multiple pregnancy.
